An Enzyme-Directed Imidazoquinoline Activated by Drug Resistance

Burt, A.J.; Hantho, J.D.; Nielsen, A.E.; Mancini, R.J. Biochemistry, 2018, 57, 15, 2184-2188

Synthetic Agonists of NOD-Like, RIG-I-Like, and C-type Lectin Receptors for Probing the Inflammatory Immune Response

Nielsen, A.E.; Hantho, J.D.; Mancini, R.J. Future Medicinal Chemistry, 2017, 9, 12, 1345-1360

Light Guided In-Vivo Activation of Innate Immune Cells with Photocaged TLR 2/6 Agonist

Ryu, K.A.; McGonnigal, B.; Moore, T.; Kargupta, T.; Mancini, R.J.; Esser-Kahn, A.P.

Nature Scientific Reports, 2017, 7, 8074-8081

An Enzyme-Directed Imidazoquinoline for Cancer Immunotherapy

Hantho, J.D.; Strayer, T.A.; Nielsen, A.E.; Mancini, R.J. ChemMedChem, 2016, 11, 22, 2496-2500

Encapsulated Hydrogels by E-beam Lithography and Their Use in Enzyme Cascade Reactions

Mancini, R.J.; Paluck, S.L.; Bat, E.; Maynard, H.D. Langmuir, 2016, 32(16), 20, 4043-4051

Controlling the Origins of Inflammation with a Photo-Active Lipopeptide Immunopotentiator

Mancini, R.J.; Stutts, L.; Moore, T.; Esser-Kahn, A. P. Angw. Chem. Int. Ed. Engl., 2015, 54, 20, 5962-5965

Stimulation of Innate Immune Cells by Light-Activated TLR7/8 Agonists

Ryu, N.; Stutts, L.; Tom, J. K.; Mancini, R. J.; Esser-Kahn, A. P. J. Am. Chem. Soc., 2014, 136, 31, 10823-10825

Directing the Immune System With Chemical Compounds

Mancini, R. J.; Stutts, L.; Ryu, K. A.; Tom, J. K.; Esser-Kahn, A. P. ACS Chem Biol., 2014, 9, 1075-1085

Covalently Coupled Immunostimulant Heterodimers

Mancini, R. J.; Tom, J. K.; Esser-Kahn, A. P. Angw. Chem. Int. Ed. Engl., 2014, 53, 189-192

Covalent Modification of Cell Surfaces with TLR Agonists

Improves Immune Stimulation

Tom, J. K.; Mancini, R. J.; Esser-Kahn, A. P. Chem. Commun., 2013, 49, 10133-10135

Trehalose Glycopolymers for Stabilization of Protein Conjugates to Environmental Stressors

Mancini, R. J.; Lee, J. Y.; Maynard, H. D. J. Am. Chem. Soc., 2012, 134, 8474-8479

Synthesis of a Photo-Caged Aminooxy Alkane Thiol

Mancini, R. J.; Li, R. C.; Tolstyka, Z. P.; Maynard, H. D. Org. Biomol. Chem., 2009, 7, 4954-4959